Using marijuana during pregnancy may cause problems for your baby before and after birth.
Yes. Before pregnancy, using marijuana can affect your fertility and make it hard for you to get pregnant. Marijuana can affect:
Is it harmful to use marijuana before pregnancy?
Yes. When you use marijuana during pregnancy, THC and other chemicals can pass through the placenta to your baby. The placenta grows in your uterus (womb) and supplies your baby with food and oxygen through the umbilical cord. Chemicals from marijuana also may pass to your baby’s brain.
Marijuana has more than 500 chemicals, including tetrahydrocannabinol (also called THC). This chemical can affect how your brain works and make it hard to think clearly. THC and other chemicals in marijuana may change your sense of sight, sound and touch.
If you use marijuana during pregnancy, your baby can have problems after birth and may need to spend time in the neonatal intensive care unit (also called NICU). A NICU is the nursey in a hospital where sick newborns get care. These problems include:
However, even cigarette smoking can also lower sperm count. Moreover, THC is a potential steroid-mimetic in that it influences LH, testosterone, and prolactin levels; hence, heavy partakers of the blessed herb who are male can sometimes develop gynecomastia – haven’t yet heard of a similar effect in women, but must have been studied by pharma or academics because of potential blockbuster (pun intended) lifestyle drug formulation. Don’t know if a THC breast cream would be as dangerous as estrogen breast creams, the latter of which should never, ever, never, be used by young women due to a logical increased risk of breast cancer.
who on the cosmic muffin’s green earth still uses the word HASH?
BTW, anandamide is intentionally taken from the Sanskrit word, ananada, meaning ‘bliss.’
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RPM, there was a 1978 paper, from Europe I think, that first kicked off this idea that smoking weed decreased sperm count (sperm density is a more accurate term). Lots of confounding variables that confuse the issue, and the subjects were called, “heavy users.” A group at SUNY Buffalo did, indeed, show in 1998 that physiologically-relevant THC interferes with fertilization via inhibiting acrosomal fusion with the egg – seems that endogenous anandamide is a positive modulator of sperm-egg fusion and THC can antagonize that positive effect.
Dey, the Dorothy Overall Wells professor of pediatrics, cell and developmental biology and pharmacology at Vanderbilt University Medical Center, and his colleagues conducted their experiments in mice. It’s known that marijuana, the most widely used illegal drug among women of childbearing age, binds to two receptors, called cannabinoid receptors 1 and 2 (CB1 and 2). These receptors are found in the brain and also in sperm, eggs and newly formed embryos. Typically, the two receptors are activated by a signaling molecule called anandamide, which is synthesized by an enzyme known as NAPE-PLD and then is degraded by another enzyme called FAAH. This balance, or “tone,” of the anandamide is crucial for the embryo to develop normally. Dey and his team suppressed FAAH activity in the mice. This increased the level of anandamide, which mimics what happens when a woman smokes marijuana and increases the level of THC, which binds to the same receptor as anandamide. The results showed that when FAAH activity is suppressed in the embryos and oviduct, anandamide levels rise, preventing the embryos from completing their passage to the uterus and compromising the pregnancy. “This is a major finding,” said Dey, “that if you block FAAH and disturb anandamide levels, there is a compromised pregnancy outcome.” . In an accompanying commentary in the journal, Herbert Schuel, professor emeritus of anatomy and cell biology at the University at Buffalo, State University of New York, said the Dey study findings “show that exogenous THC can swamp endogenous anandamide signaling systems,” affecting many processes in the body. And Schuel offered another warning: Several drugs in development to suppress appetite work by modifying anandamide signaling. Since many women of reproductive age take weight-loss drugs, he suggested that these drugs must be carefully evaluated to determine the long-term effects on women.
Nyahahaaaa. you said stone.
There will be no discussion of killing birds on this here site. 🙂